アルツハイマー病モデルにおけるスプライシング制御不全についてのオスロ大学Akershus大学病院との共同研究の論文が、Science Advances誌にオンライン掲載されました。

Ruixue Ai, Lipeng Mao, Xurui Jin, Carlos Campos-Marques, Shi-qi Zhang, Junping Pan, Maria Jose Lagartos-Donate, Shu-Qin Cao, Beatriz Barros-Santos, Rita Nóbrega-Martins, Filippos Katsaitis, Guang Yang, Chenglong Xie, Xiongbin Kang, Pingjie Wang, Manuele Novello, Yang Hu, Linda Hildegard Bergersen, Jon Storm-Mathisen, Hidehito Kuroyanagi, Beatriz Escobar Doncel, Noemí Villaseca González, Farrukh Abbas Chaudhry, Zeyuan Wang, Qiang Zhang, Guang Lu, Ioannis Sotiropoulos, Zhangming Niu, Guobing Chen, Rajeevkumar Raveendran Nair, Joana Margarida Silva*, Oscar Junhong Luo*, Evandro Fei Fang*. 

"NAD⁺ reverses Alzheimer’s neurological deficits via regulating differential alternative RNA splicing of EVA1C."

Science Advances 11 (45): eady9811 (2025).