Publications

2025

Original Research Articles

• "NAD+ reverses Alzheimer’s neurological deficits via regulating differential alternative RNA splicing of EVA1C. "
  Ruixue Ai, Lipeng Mao, Xurui Jin, Carlos Campos-Marques, Shi-qi Zhang, Junping Pan, Maria Jose Lagartos-Donate, Shu-Qin Cao, Beatriz Barros-Santos, Rita Nóbrega-Martins, Filippos Katsaitis, Guang Yang, Chenglong Xie, Xiongbin Kang, Pingjie Wang, Manuele Novello, Yang Hu, Linda Hildegard Bergersen, Jon Storm-Mathisen, Hidehito Kuroyanagi, Beatriz Escobar Doncel, Noemí Villaseca González, Farrukh Abbas Chaudhry, Zeyuan Wang, Qiang Zhang, Guang Lu, Ioannis Sotiropoulos, Zhangming Niu, Guobing Chen, Rajeevkumar Raveendran Nair, Joana Margarida Silva*, Oscar Junhong Luo*, Evandro Fei Fang*.
  Science Advances 11, 45, eady9811 (2025).

  • DOI: 10.1126/sciadv.ady9811
• "Q373fs variant of RBM20 affects splicing and expression of cardiac-related genes and cardiac function: human sudden death case and mouse experiments"
  Aya Miura, Takuma Yamamoto*, Mai Imasaka, Michihiko Sugimoto, Yoshiro Naito, Hiroshi Nishiura, Minori Nishiguchi, Kazuhisa Funayama, Yuri Yamasu, Akihide Koyama, Hisakazu Takatsuka, Hidehito Kuroyanagi, Masaki Ohmuraya, Hajime Nishio
  Human Molecular Genetics, ddaf157 (2025).

  • DOI: 10.1093/hmg/ddaf157
• "UNC5B is an isoform-dependent target for ectodomain shedding."
  Kotaro Sugimoto, Eichi Watabe, Mio Takuma, Kaname Nagahara, Toshinori Sawano, Mihoko Kajita, Junichi Takagi, Hidehito Kuroyanagi, Kyoko Shirakabe.
  The Journal of Biochemistry 178, 4, 267–275 (2025).

  • DOI: 10.1093/jb/mvaf043
• "Cytoplasmic mutant RBM20 causes arrhythmogenicity in murine atria."
  Kensuke Ihara, Satoshi Iwamiya, Masaki Ikuta, Yurie Soejima, Yuichi Hiraoka, Atsushi Nakano, Susumu Minamisawa, Tetsushi Furukawa, Hidehito Kuroyanagi, Tetsuo Sasano
  Journal of Molecular and Cellular Cardiology 205, 1-12 (2025).

  • DOI: 10.1016/j.yjmcc.2025.06.001
• "Profiling of RBM20-Regulated CaMKIIδ Splice Variants Across the Heart, Skeletal Muscle, and Olfactory Bulbs."
  Yui MAEDA, Yuri YAMASU and Hidehito KUROYANAGI
  Genes to Cells 30, 3, e70021 (2025).

  • DOI: 10.1111/gtc.70021

PrePrint

• "Comprehensive Profiling of RBM20-Regulated CaMKIIδ Splice Variants Across the Heart, Skeletal Muscle, and Olfactory Bulbs."
  Yui Maeda, Yuri Yamasu, Hidehito Kuroyanagi
  bioRxiv (2025).

  • DOI: 10.1101/2025.02.27.640675